BDBM29581 isatin sulfonamide, 16a

SMILES O=C1N(Cc2ccccc2)c2ccc(cc2C1=O)S(=O)(=O)N1CCC1

InChI Key InChIKey=HPLZVLGCPPHPFD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 29581   

TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29581(isatin sulfonamide, 16a)
Affinity DataIC50: 114nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

LigandPNGBDBM29581(isatin sulfonamide, 16a)
Affinity DataIC50: 115nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

LigandPNGBDBM29581(isatin sulfonamide, 16a)
Affinity DataIC50: 132nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

LigandPNGBDBM29581(isatin sulfonamide, 16a)
Affinity DataIC50: 9.83E+3nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Washington University

LigandPNGBDBM29581(isatin sulfonamide, 16a)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

LigandPNGBDBM29581(isatin sulfonamide, 16a)
Affinity DataIC50: 5.00E+4nMAssay Description:The caspase enzymatic activity was determined by measuring the accumulation of a fluorogenic product. All assays were prepared in 96-well format. Rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed