BDBM295994 US10112939, Example 35

SMILES CCNC(=O)c1cccc(C2CCCN2C(=O)c2ccc(-c3cn[nH]c3)c(OC)c2)c1

InChI Key InChIKey=UTEQPZYSVVAGFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295994   

TargetRho-associated protein kinase 2(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 295994BDBM295994(US10112939, Example 35)
Affinity DataIC50: 4.89nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent