BDBM296052 US10112939, Example 92

SMILES COc1cc(C(=O)N2C[C@H](O)C[C@@H]2c2ccccc2F)ccc1-c1cn[nH]c1

InChI Key InChIKey=XOONWRSAVXKANI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296052   

TargetRho-associated protein kinase 2(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 296052BDBM296052(US10112939, Example 92)
Affinity DataIC50: 8.03nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent