BDBM297410 US10117858, Example 17

SMILES C[C@@](O)(CNC(=O)c1nc(c(cc1N)C(F)(F)F)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=DOVVSHMLCFFGGB-SECBINFHSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297410   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM297410(US10117858, Example 17)
Affinity DataEC50:  10nMAssay Description:Fischer Rat Thyroid (FRT) epithelial cells, stably expressing human ΔF508-CFTR were used as monolayer cultures on permeable supports. Cl− ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent