BDBM29744 hydroxyethylene tripeptide inhibitor, 1
SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)CCC(C)C
InChI Key InChIKey=XTRMRNMVFXWTCC-MLNNCEHLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 29744
Affinity DataIC50: 1.40E+3nMpH: 4.5 T: 22°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 370nMpH: 3.1 T: 22°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1 expressed in CHO cells expressing human recombinant APP assessed as amyloid beta40 aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair