BDBM297489 US10117944, Compound SDC-TRAP-0240

SMILES CCNC(=O)c1nnc(-c2cc(C(C)C)c(O)cc2O)n1-c1ccc2n(CCC3CCN(CC3)C(=O)c3ccc(cc3)C3(C)OB(OC3(C)C)[C@H](CC(C)C)NC(O)[C@H](Cc3ccccc3)NC(=O)c3cnccn3)ccc2c1

InChI Key InChIKey=NNGJYXORWKLXIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297489   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Madrigal Pharmaceuticals

US Patent
LigandPNGBDBM297489(US10117944, Compound SDC-TRAP-0240)
Affinity DataIC50: 5.00E+3nMAssay Description:HER2 has emerged as a key target for anticancer drugs due to its intrinsic involvement in the phosphatidylinositol-3-kinase-Akt/protein kinase B (PI3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent