BDBM297578 2-cyclopropyl-4-[4-(2-methoxy- phenyl)-piperidin-1-yl]-6-(3- methoxy-pyrrolidin-1-yl)- quinazoline::US10118902, Example 80::US10584103, Example 80

SMILES COC1CCN(C1)c1ccc2nc(nc(N3CCC(CC3)c3ccccc3OC)c2c1)C1CC1

InChI Key InChIKey=JPWQBXUIRBWWIL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297578   

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297578(US10118902, Example 80 | 2-cyclopropyl-4-[4-(2-met...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297578(US10118902, Example 80 | 2-cyclopropyl-4-[4-(2-met...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent