BDBM297669 (1-Fluoro-cyclopropyl)-{7-fluoro- 6-[(2-hydroxy-ethyl)-methyl- amino]-4-[4-(2-methoxy-phenyl)- piperidin-1-yl]-quinazolin-2-yl}- methanone::US10118902, Example 171::US10584103, Example 171

SMILES COc1ccccc1C1CCN(CC1)c1nc(nc2cc(F)c(cc12)N(C)CCO)C1(F)CC1

InChI Key InChIKey=HHAPARWQHIFMKW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297669   

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297669(US10118902, Example 171 | (1-Fluoro-cyclopropyl)-{...)
Affinity DataEC50: <500nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297669(US10118902, Example 171 | (1-Fluoro-cyclopropyl)-{...)
Affinity DataEC50: <500nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent