BDBM297701 2-{[8-Fluoro-4-[4-(3-methoxy- pyrazin-2-yl)-piperidin-1-yl]-2- (1-methyl-cyclopropyl)- quinazolin-6-yl]-methyl-amino}- ethanol::US10118902, Example 204::US10584103, Example 204

SMILES COc1nccnc1C1CCN(CC1)c1nc(nc2c(F)cc(cc12)N(C)CCO)C1(C)CC1

InChI Key InChIKey=VLJIIIOCWBYIQC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297701   

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297701(US10118902, Example 204 | 2-{[8-Fluoro-4-[4-(3-met...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297701(US10118902, Example 204 | 2-{[8-Fluoro-4-[4-(3-met...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent