BDBM297704 2-{[2-(1-Fluoro-cyclopropyl)-4- (2-methoxy-3',4',5',6'-tetrahydro- 2'H-[3,4']bipyridinyl-1'-yl)- quinazolin-6-yl]-methyl-amino}- ethanol::US10118902, Example 207::US10584103, Example 207

SMILES COc1ncccc1C1CCN(CC1)c1nc(nc2ccc(cc12)N(C)CCO)C1(F)CC1

InChI Key InChIKey=IPBWPASLBVYBRX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297704   

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297704(US10118902, Example 207 | 2-{[2-(1-Fluoro-cyclopro...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297704(US10118902, Example 207 | 2-{[2-(1-Fluoro-cyclopro...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent