BDBM297825 3-(3-Chlorophenyl)-7-(piperidin-4-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one hydrochloride::US10118930, Example 48

SMILES O=c1cc(C2CCNCC2)n2ncc(-c3cccc(Cl)c3)c2[nH]1

InChI Key InChIKey=MEHCXKHOTKAHFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297825   

TargetTissue-type plasminogen activator(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 297825BDBM297825(US10118930, Example 48 | 3-(3-Chlorophenyl)-7-(pip...)
Affinity DataIC50: 14nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent