BDBM298065 3-[5-(2-chlorobenzyl)-1,3,4-oxadiazol-2-yl]-7-(piperidin-4-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one hydrochloride::US10118930, Example 276

SMILES O=c1cc(C2CCNCC2)n2ncc(-c3nnc(Cc4ccccc4Cl)o3)c2[nH]1

InChI Key InChIKey=TWDNXLAEXJJVEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 298065   

TargetTissue-type plasminogen activator(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 298065BDBM298065(US10118930, Example 276 | 3-[5-(2-chlorobenzyl)-1,...)
Affinity DataIC50: 14nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent