BDBM298184 Rel-3-{5-[(1R,2S)-2-methylcyclopentyl]-1,2,4-oxadiazol-3-yl}-7-(piperidin-4-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one hydrochloride::US10118930, Example 387

SMILES CC1CCCC1c1nc(-c2cnn3c(C4CCNCC4)cc(=O)[nH]c23)no1

InChI Key InChIKey=ATUBYBPXVCJCET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 298184   

TargetTissue-type plasminogen activator(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 298184BDBM298184(US10118930, Example 387 | Rel-3-{5-[(1R,2S)-2-meth...)
Affinity DataIC50: 10nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent