BDBM298802 2-amino-5-(1-methyl-1H-pyrazol-4-yl)-N-((1S,2S)-2-((4′-(1-(4-methylpiperazin-1-yl)ethyl)-[1,1′-biphenyl]-4-yl)methoxy)cyclopentyl)nicotinamide::US10125118, Example 208::US10947215, Example 208

SMILES CC(N1CCN(C)CC1)c1ccc(cc1)-c1ccc(CO[C@H]2CCC[C@@H]2NC(=O)c2cc(cnc2N)-c2cnn(C)c2)cc1

InChI Key InChIKey=MXKYSMZRKIEXAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298802   

TargetTyrosine-protein kinase Mer/receptor UFO(Human)
Dong-A Socio Holdings

US Patent
LigandPNGBDBM298802(US10125118, Example 208 | 2-amino-5-(1-methyl-1H-p...)
Affinity DataIC50: 10nMAssay Description:For the SAR (structure-activity relationship) and compound screening, LanthaScreen TR-FRET (Time-Resolved fluorescence energy transfer) assay was emp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Dong-A Socio Holdings

US Patent
LigandPNGBDBM298802(US10125118, Example 208 | 2-amino-5-(1-methyl-1H-p...)
Affinity DataIC50: 10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent