BDBM300130 5-Cyclopropyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(4-methoxyphenyl)methyl]triazolo [4,5-d]pyrimidine::US9593123, Example 2

SMILES COc1ccc(Cn2nnc3c(nc(nc23)C2CC2)N2CCC(F)(F)C2)cc1

InChI Key InChIKey=ASXIIPGBHYPUQE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300130   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300130(5-Cyclopropyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(...)
Affinity DataEC50:  6.40nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300130(5-Cyclopropyl-7-(3,3-difluoropyrrolidin-1-yl)-3-[(...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent