BDBM300139 3-[(2-Chlorophenyl)methyl]-N-cyclobutyl-7-(3,3-difluoropyrrolidin-1-yl)triazolo[4,5-d]pyrimidin-5-amine::US9593123, Example 11

SMILES FC1(F)CCN(C1)c1nc(NC2CCC2)nc2n(Cc3ccccc3Cl)nnc12

InChI Key InChIKey=JFLDYVFOYCWJCA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300139   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300139(3-[(2-Chlorophenyl)methyl]-N-cyclobutyl-7-(3,3-dif...)
Affinity DataEC50:  2.60nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300139(3-[(2-Chlorophenyl)methyl]-N-cyclobutyl-7-(3,3-dif...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent