BDBM300189 (3S)-1-[3-[(2-Chlorophenyl)methyl]-5-(2,2,2-trifluoroethoxy)triazolo[4,5-d]pyrimidin-7-yl]pyrrolidin-3-ol::US9593123, Example 60

SMILES O[C@H]1CCN(C1)c1nc(OCC(F)(F)F)nc2n(Cc3ccccc3Cl)nnc12

InChI Key InChIKey=ZMEQBECXADLSQF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300189   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300189((3S)-1-[3-[(2-Chlorophenyl)methyl]-5-(2,2,2-triflu...)
Affinity DataEC50:  0.800nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300189((3S)-1-[3-[(2-Chlorophenyl)methyl]-5-(2,2,2-triflu...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent