BDBM300199 3-[(3-Chloropyridin-2-yl)methyl]-7-(3,3-difluoropyrrolidin-1-yl)-5-[(2S)-1,1,1-trifluoropropan-2-yl]oxytriazolo[4,5-d]pyrimidine::US9593123, Example 70

SMILES C[C@H](Oc1nc(N2CCC(F)(F)C2)c2nnn(Cc3ncccc3Cl)c2n1)C(F)(F)F

InChI Key InChIKey=GWDCGLBNWLRGAQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300199   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300199(3-[(3-Chloropyridin-2-yl)methyl]-7-(3,3-difluoropy...)
Affinity DataEC50:  5.10nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300199(3-[(3-Chloropyridin-2-yl)methyl]-7-(3,3-difluoropy...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent