BDBM300541 N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[2-(morpholin-4-yl)propanoyl]amino}-4-(trifluoromethoxy)benzamide::US10130633, Example 111

SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccc(N)cc1

InChI Key InChIKey=DQJNFUCPLJAFHW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 300541   Sort by

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300541(N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[2-(morpholin...)
Affinity DataIC50: 32.2nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300541(N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[2-(morpholin...)
Affinity DataIC50: 5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300541(N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[2-(morpholin...)
Affinity DataIC50: 58nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300541(N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[2-(morpholin...)
Affinity DataIC50: 5.00E+4nMAssay Description:HEK293 cells were cotransfected with the FOP control vector and pcDNA3. The FOP vector is identical to the TOP construct, but it contains instead of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent