BDBM300677 N-[6-(3-fluorophenyl)pyridin-3- yl]-3-{[2-(8-oxa-3- azabicyclo[3.2.1]oct-3- yl)propanoyl]amino}-4- (trifluoromethoxy)benzamide::US10130633, Example 247::US10130633, Example 248

SMILES CC(N1CC2CCC(C1)O2)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cccc(F)c1

InChI Key InChIKey=XTYSNFAOAGFDBE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 300677   Sort by

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300677(US10130633, Example 248 | N-[6-(3-fluorophenyl)pyr...)
Affinity DataIC50: 11nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300677(US10130633, Example 248 | N-[6-(3-fluorophenyl)pyr...)
Affinity DataIC50: 7.20E+3nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300677(US10130633, Example 248 | N-[6-(3-fluorophenyl)pyr...)
Affinity DataIC50: 340nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300677(US10130633, Example 248 | N-[6-(3-fluorophenyl)pyr...)
Affinity DataIC50: 5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent