BDBM300707 (2S,4S)-4-[(5-Chloro-2H-[1,2,4]triazole-3-carbonyl)amino]-5-(3′-fluorobiphenyl-4-yl)-2-hydroxymethyl-pentanoic acid::US10130642, Example 3B

SMILES O=C(N[C@H](Cc1ccc(-c2cccc(F)c2)cc1)C[C@@H](CO)C(=O)O)c1nc(Cl)n[nH]1

InChI Key InChIKey=WMIDDCHRAIMDGR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300707   

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandChemical structure of BindingDB Monomer ID 300707BDBM300707((2S,4S)-4-[(5-Chloro-2H-[1,2,4]triazole-3-carbonyl...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent