BDBM301101 4-[2-(4-aminopiperidin-1-yl)-5-[2-(3- hydroxyoxolan-3- yl)ethynyl]pyrimidin-4-yl]-2- fluorobenzonitrile::US10131664, Example 94

SMILES NC1CCN(CC1)c1ncc(C#CC2(O)CCOC2)c(n1)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=UAVRZVFRPDYUAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301101   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 301101BDBM301101(4-[2-(4-aminopiperidin-1-yl)-5-[2-(3- hydroxyoxola...)
Affinity DataIC50: 10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent