BDBM301918 N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-4-phenylcyclohexanecarboxamide::US9598387, Compound 103::US9969743, 103

SMILES CC(C)(C)c1nc(N2CCN(CCCCNC(=O)C3CCC(c4ccccc4)CC3)CC2)cc(C(F)(F)F)n1

InChI Key InChIKey=IHTMZOURUQYLLI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 301918   

TargetD(3) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 301918BDBM301918(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  9.40nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 301918BDBM301918(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  9.40nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 301918BDBM301918(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  1.51E+3nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 301918BDBM301918(N-(4-(4-(2-(tert-Butyl)-6-(trifluoromethyl)pyrimid...)
Affinity DataKi:  1.51E+3nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent