BDBM302591 2-(3-Chlorophenyl)-N5- (4-fluorophenyl)-6,7- dihydropyrazolo[1,5-a]pyrazine- 3,5(4H)-dicarboxamide::US9598423, Example 157

SMILES NC(=O)c3c2CN(C(=O)Nc1ccc(F)cc1)CCn2nc3c4cccc(Cl)c4

InChI Key InChIKey=VQFUQLXFYRTQDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302591   

TargetCasein kinase I isoform epsilon(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302591(2-(3-Chlorophenyl)-N5- (4-fluorophenyl)-6,7- dihyd...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302591(2-(3-Chlorophenyl)-N5- (4-fluorophenyl)-6,7- dihyd...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent