BDBM302593 2-(3-Chlorophenyl)-N5- (4-cyano-3-(trifluoromethyl) phenyl)-6,7-dihydropyrazolo [1,5-a]pyrazine-3,5(4H)- dicarboxamide::US9598423, Example 159

SMILES [C-]#[N+]c4ccc(NC(=O)N3CCn2nc(c1cccc(Cl)c1)c(C(N)=O)c2C3)cc4C(F)(F)F

InChI Key InChIKey=RZFCHHDCVDXVSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302593   

TargetCasein kinase I isoform epsilon(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302593(2-(3-Chlorophenyl)-N5- (4-cyano-3-(trifluoromethyl...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302593(2-(3-Chlorophenyl)-N5- (4-cyano-3-(trifluoromethyl...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent