BDBM302595 2-(3-Chlorophenyl)-N5- (3-cyanophenyl)-6,7- dihydropyrazolo[1,5-a] pyrazine-3,5(4H)-dicarboxamide::US9598423, Example 161

SMILES N#Cc4cccc(NC(=O)N3CCn2nc(c1cccc(Cl)c1)c(C(N)=O)c2C3)c4

InChI Key InChIKey=JJODGKVBTBXIFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302595   

TargetCasein kinase I isoform epsilon(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302595(2-(3-Chlorophenyl)-N5- (3-cyanophenyl)-6,7- dihydr...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302595(2-(3-Chlorophenyl)-N5- (3-cyanophenyl)-6,7- dihydr...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent