BDBM302601 2-(3-Chlorophenyl)-N5- (3-fluorophenyl)-6,7- dihydropyrazolo[1,5-a] pyrazine-3,5(4H)-dicarboxamide::US9598423, Example 167

SMILES NC(=O)c3c2CN(C(=O)Nc1cccc(F)c1)CCn2nc3c4cccc(Cl)c4

InChI Key InChIKey=BBBNUOAAZAJOOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302601   

TargetCasein kinase I isoform epsilon(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302601(2-(3-Chlorophenyl)-N5- (3-fluorophenyl)-6,7- dihyd...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302601(2-(3-Chlorophenyl)-N5- (3-fluorophenyl)-6,7- dihyd...)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent