BDBM302606 US9598423, Example 172

SMILES N#Cc4ccc(NC(=O)N3CCn2nc(c1ccc(F)c(Cl)c1)c(C(N)=O)c2C3)cc4

InChI Key InChIKey=RRBODDWUULPZFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302606   

TargetCasein kinase I isoform epsilon(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302606(US9598423, Example 172)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetCasein kinase I isoform delta(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM302606(US9598423, Example 172)
Affinity DataIC50: 10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent