BDBM303206 US10137122, Compound 80

SMILES Cc1[nH]nc2c1[C@H](c1ccccc1Br)C1=C(CC(C)(C)CC1=O)N2

InChI Key InChIKey=AOQLEKLYMVXVEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303206   

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 303206BDBM303206(US10137122, Compound 80)
Affinity DataIC50: 100nMAssay Description:A solution of 4× inhibitor (5 μL), 4× substrate/ATP-Metal solution (5 μL), and 2× Kinase solution (10 μL) was prepared with assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 303206BDBM303206(US10137122, Compound 80)
Affinity DataIC50: 100nMAssay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen Eu Kinase Binding Assay. In this assay, His-tagged recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent