BDBM303277 2-amino-N-[(2,2,- difluoro-1,3- benzodioxol-4- yl)methyl]-8-methoxy- quinazoline-4- carboxamide::US10138212, Example 42

SMILES COc1cccc2c(C(=O)NCc3cccc4c3OC(F)(F)O4)nc(N)nc12

InChI Key InChIKey=BJAHYKBWTKILAC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303277   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 303277BDBM303277(2-amino-N-[(2,2,- difluoro-1,3- benzodioxol-4- yl)...)
Affinity DataKi:  5.30nMAssay Description:Binding affinities of compounds of the invention for the human A2a receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent