BDBM30332 Naphthoic acid-based analog, 1e

SMILES CC(C)c1onc(c1COc1ccc(cc1)-c1ccc2cccc(C(O)=O)c2c1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=KVNUJCGFGCPUOA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30332   

TargetBile acid receptor(Human)
Gsk

LigandPNGBDBM30332(Naphthoic acid-based analog, 1e)
Affinity DataEC50:  3.30E+3nMAssay Description:The cell-based assay measures the ligand-mediated luminescense resulting from FXR-induced transcription of a luciferase reporter. FXR and the lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Human)
Gsk

LigandPNGBDBM30332(Naphthoic acid-based analog, 1e)
Affinity DataEC50:  2.30E+3nMpH: 7.5 T: 22°CAssay Description:The assay measures ligand-mediated interaction of the SRC-1 peptide with the FXR ligand binding domain, using biotinylated FXR LBD coupled to allophy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed