BDBM30367 piperidinyl glycine derivative, 24d

SMILES COc1ccc(cc1)-c1ccc(s1)S(=O)(=O)N[C@H](C1CCN(CC1)C(=O)OC(C)C)C(O)=O

InChI Key InChIKey=DLLCDWXNWWRIFJ-HXUWFJFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30367   

TargetInterstitial collagenase(Human)
Novartis

LigandPNGBDBM30367(piperidinyl glycine derivative, 24d)
Affinity DataIC50:  950nMT: 25°CAssay Description:Test compounds were serially diluted in deep well plates, and an aliquot of the inhibitor solutions was transferred to a Biomek deep well plate conta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCollagenase 3(Human)
Novartis

LigandPNGBDBM30367(piperidinyl glycine derivative, 24d)
Affinity DataIC50:  0.600nMpH: 7.5 T: 22°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed