BDBM303913 US10138241, Example 100::US11130754, Example 100

SMILES COc1cc2ncc(-n3cnc(c3)-c3cc(C(=O)NC4CC4)c(F)cc3C)n2cc1C1(F)CCN(C)CC1

InChI Key InChIKey=DIRAUFQRLWBHFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303913   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303913(US10138241, Example 100 | US11130754, Example 100)
Affinity DataIC50:  2.40nMAssay Description:Method: In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303913(US10138241, Example 100 | US11130754, Example 100)
Affinity DataIC50:  2.40nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent