BDBM303951 US10138242, Compound 37

SMILES COc1ccc(CN2CCc3c(C2)c(nn3-c2ccccc2)C(=O)NCc2cccc3ccccc23)c2ccccc12

InChI Key InChIKey=LZFIYOUXLOOKBI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303951   

TargetPEX5-related protein/Peroxisomal membrane protein PEX14(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM303951(US10138242, Compound 37)
Affinity DataIC50:  240nMAssay Description:Antitrypanosomal activity was tested on T. brucei brucei bloodstream from parasites (strainżLister 427, VATMITat 1.2). Stock solutions of compounds (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPEX5-related protein/Peroxisomal membrane protein PEX14(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM303951(US10138242, Compound 37)
Affinity DataEC50:  7.61E+3nMAssay Description:The assay uses two types of beads: donor beads are coupled with streptavidin, and acceptor beads are coupled with an anti His-tag antibody. Upon exci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent