BDBM304137 USRE47141, Example 59

SMILES [C-]#[N+]c1ccccc1NCc1nc(-c2ccc3ncnn3c2)c(-c2cccc(C)n2)[nH]1

InChI Key InChIKey=MXXUKYHPXJPPBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304137   

TargetTGF-beta receptor type-1(Human)
Ewha University—Industry Collaboration Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 304137BDBM304137(USRE47141, Example 59)
Affinity DataIC50: 19.5nMAssay Description:ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent