BDBM304140 USRE47141, Example 64

SMILES [C-]#[N+]c1c(C#N)cccc1NCc1nc(-c2ccc3ncnn3c2)c(-c2cccc(C)n2)[nH]1

InChI Key InChIKey=RMHWQFUISDEBBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304140   

TargetTGF-beta receptor type-1(Human)
Ewha University—Industry Collaboration Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 304140BDBM304140(USRE47141, Example 64)
Affinity DataIC50: 20.6nMAssay Description:ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent