BDBM304498 US10144729, Example 2b

SMILES O=C(NS(=O)(=O)C1CCCCC1)c1ccc([C@@H]2C[C@H]2c2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C3CC3)cc2Cl)cc1

InChI Key InChIKey=MMIDJTZHRPXCFR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304498   

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304498BDBM304498(US10144729, Example 2b)
Affinity DataEC50:  550nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent