BDBM304716 US10144729, Example 2d

SMILES CC(C)(C)c1ccc(S(=O)(=O)NC(=O)Nc2ccc([C@@H]3C[C@H]3c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CC4)cc3Cl)cc2)cc1

InChI Key InChIKey=LLURXRCAJHOCRV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304716   

TargetBile acid receptor(Human)
Enanta Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304716BDBM304716(US10144729, Example 2d)
Affinity DataEC50:  550nMAssay Description:The assay utilizes non-human mammalian cells, CHO (Chinese hamster ovary) cells engineered to express human NR1H4 protein (referred to as FXR). Repor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent