BDBM30547 US8846698, 583

SMILES Nc1ncc2c(cn(c2n1)C12CC(C1)C2)C(=O)c1cncc(NC(=O)Cc2ccc(Cl)cn2)c1

InChI Key InChIKey=CPUXQZALGBLQTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30547   

TargetHigh affinity nerve growth factor receptor(Human)
Pfizer

US Patent
LigandPNGBDBM30547(US8846698, 583)
Affinity DataIC50:  0.681nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so...More data for this Ligand-Target Pair
In DepthDetails US Patent