BDBM306728 N-(2-(4- ((1R,3R)-2- (2,2-difluoro- 3-methoxy- propyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 3,5-difluoro- phenoxy) ethyl)-3- fluoropropan- 1-amine::US10149839, Example 14

SMILES COCC(F)(F)CN1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cc(OCCNCCCF)cc1F

InChI Key InChIKey=JDZXVHSNKVLNKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306728   

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 306728BDBM306728(US10149839, Example 14 | N-(2-(4- ((1R,3R)-2- (2,2...)
Affinity DataIC50: 2.5nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent