BDBM306736 3-fluoro-N-(2- (3-fluoro-4- ((1R,3R)-2-((3- fluorooxetan- 3-yl)methyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)phenoxy) ethyl)propan- 1-amine::US10149839, Example 22

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)COC1)c1ccc(OCCNCCCF)cc1F

InChI Key InChIKey=NYEDQYIZMHAQHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306736   

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 306736BDBM306736(US10149839, Example 22 | 3-fluoro-N-(2- (3-fluoro-...)
Affinity DataIC50: 1.10nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent