BDBM306741 3-fluoro-N- ((S)-1-(4- ((1R,3R)-2-((3- fluorooxetan- 3-yl)methyl)-3- methyl-2,3,4,9- tetrahydro- 1H-pyrido[3,4- b]indol-1- yl)phenoxy) propan-2- yl)propan-1- amine::US10149839, Example 27

SMILES C[C@@H](COc1ccc(cc1)[C@H]1N(CC2(F)COC2)[C@H](C)Cc2c1[nH]c1ccccc21)NCCCF

InChI Key InChIKey=AKLIKHYLAGCESR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306741   

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 306741BDBM306741(US10149839, Example 27 | 3-fluoro-N- ((S)-1-(4- ((...)
Affinity DataIC50: 2.20nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent