BDBM306779 2,2-difluoro-3- ((1R,3R)-1-(6- ((2-((3- fluoropropyl) amino)ethyl) amino)-4- methoxy- pyridin-3-yl)- 3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10149839, Example 65

SMILES COc1cc(NCCNCCCF)ncc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21

InChI Key InChIKey=JZPNHIVVQQJGAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306779   

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 306779BDBM306779(US10149839, Example 65 | 2,2-difluoro-3- ((1R,3R)-...)
Affinity DataIC50: 2.40nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent