BDBM306781 N1-(5- ((1R,3R)-2- (2,2- difluoroethyl)- 3-methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 4-methoxy- pyridin-2- yl)-N2-(3- fluoropropyl) ethane-1,2- diamine::US10149839, Example 67

SMILES COc1cc(NCCNCCCF)ncc1[C@H]1N(CC(F)F)[C@H](C)Cc2c1[nH]c1ccccc21

InChI Key InChIKey=LMGXBNSNQWLKCY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306781   

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 306781BDBM306781(US10149839, Example 67 | N1-(5- ((1R,3R)-2- (2,2- ...)
Affinity DataIC50: 2.5nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent