BDBM306783 2,2-difluoro-3- ((1S,3R)-1-(5- (2-((3- fluoropropyl) amino)ethoxy) pyrazin-2- yl)-3-methyl- 1,3,4,9- tetrahydro-2H- pyrido[3,4- b]indol-2- yl)propan-1-ol::US10149839, Example 69

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1cnc(OCCNCCCF)cn1

InChI Key InChIKey=YPRUDQFJRYVVKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306783   

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 306783BDBM306783(US10149839, Example 69 | 2,2-difluoro-3- ((1S,3R)-...)
Affinity DataIC50: 0.970nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent