BDBM306791 N-(2-((5- ((1R,3R)-2- (2,2-difluoro- propyl)-3- methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1-yl)- 6-methoxy- pyridin-2- yl)oxy)ethyl)- 3-fluoro- propan-1-amine::US10149839, Example 77

SMILES COc1nc(OCCNCCCF)ccc1[C@H]1N(CC(C)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21

InChI Key InChIKey=BAGTWEJYAMHNSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306791   

TargetEstrogen receptor(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 306791BDBM306791(US10149839, Example 77 | N-(2-((5- ((1R,3R)-2- (2,...)
Affinity DataIC50: 2.10nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent