BDBM307491 US10150728, Example I-734

SMILES C[C@@H](CO[C@H]1CC[C@@H](CC1)Oc1nc2c(F)cc(OC3CC3)cc2n1C)NC(C)=O

InChI Key InChIKey=PKIZITQRNOQNPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 307491   

TargetAcetyl-CoA carboxylase 2(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 307491BDBM307491(US10150728, Example I-734 | US12521375, Compound I...)
Affinity DataIC50: 3.80nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 307491BDBM307491(US10150728, Example I-734 | US12521375, Compound I...)
Affinity DataIC50: 4nMAssay Description:Recombinant human ACC1 and recombinant human ACC2, which were prepared by the method mentioned above, were preincubated with assay buffer solution (5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 307491BDBM307491(US10150728, Example I-734 | US12521375, Compound I...)
Affinity DataIC50: 1.70E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details US Patent