BDBM307537 5-(3-(Bicyclo[1.1.1]pentan-1-ylcarbamoyl)-4-fluorophenyl)-2-(4-fluoro phenyl)-N-methyl-6-(2,2,2-trifluoroethoxy)benzofuran-3-carboxamide::US10150747, Example 4

SMILES CNC(=O)c1c(oc2cc(OCC(F)(F)F)c(cc12)-c1ccc(F)c(c1)C(=O)NC12CC(C1)C2)-c1ccc(F)cc1

InChI Key InChIKey=KPHVTFUCHMXCRL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307537   

TargetGenome polyprotein(HCV)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307537(US10150747, Example 4 | 5-(3-(Bicyclo[1.1.1]pentan...)
Affinity DataIC50: 3.88nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307537(US10150747, Example 4 | 5-(3-(Bicyclo[1.1.1]pentan...)
Affinity DataEC50:  8.61nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent