BDBM307548 N-(bicyclo[1.1.1]pentan-1-yl)-5-(6-ethoxy-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-5-yl)-2-methoxynicotinamide::US10150747, Example 15

SMILES CCOc1cc2oc(c(C(=O)NC)c2cc1-c1cnc(OC)c(c1)C(=O)NC12CC11CC1C2)-c1ccc(F)cc1

InChI Key InChIKey=GOAWCMFBIKMWKZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307548   

TargetGenome polyprotein(HCV)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307548(US10150747, Example 15 | N-(bicyclo[1.1.1]pentan-1...)
Affinity DataIC50: 2.48nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307548(US10150747, Example 15 | N-(bicyclo[1.1.1]pentan-1...)
Affinity DataEC50:  7.03nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent