BDBM307553 6-(2,2-difluoroethoxy)-2-(4-fluorophenyl)-N-methyl-5-(3-((1-(pyrimidin-2-yl)cyclopropyl)carbamoyl)phenyl)benzofuran-3-carboxamide::US10150747, Example 20

SMILES CNC(=O)c1c(oc2cc(OCC(F)F)c(cc12)-c1cccc(c1)C(=O)NC1(CC1)c1ncccn1)-c1ccc(F)cc1

InChI Key InChIKey=SPITXUBONFPKQZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307553   

TargetGenome polyprotein(HCV)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307553(US10150747, Example 20 | 6-(2,2-difluoroethoxy)-2-...)
Affinity DataIC50: 4.54nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent

TargetGenome polyprotein(HCV)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307553(US10150747, Example 20 | 6-(2,2-difluoroethoxy)-2-...)
Affinity DataEC50:  6.79nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent